Aurora Ruiz-Herrera Moreno

Personal information

Email: aurora.ruizherrera@uab.cat

Unit: Genomics in Evolution and Disease

Group: Genome Integrity and Instability

Category: Professor Agregat

Lab phone: 935811379

Academic information and publications


Academic background

  • Ph.D. in Cell Biology, Universitat Autónoma de Barcelona (UAB), Barcelona, Spain.
  •  B.Sc. Majors: Cell Biology. UAB, Barcelona (Spain). June 1998. 

Current position and relevant tasks

  • Professora Agregada. Department of Cell Biology, UAB. Since September 2013.
  • Coordinator of the postgraduate course “Cytogenetics and Evolution” in the PhD program in Cell Biology, UAB Since 2009.
  •  Coordinator of the Histology section of course “Cell Biology and Histology” conducted in two Graduate Schools (Genetics and Microbiology), UAB. Since 2009.
  • Member of the teaching team of (i) the postgraduate course “Principles of Human Evolution” in the PhD program in Human Biology, UAB (Spain) and (ii) pre-graduate courses conducted in three Grad Schools (Graduate in Biology, Genetics and Microbiology), UAB. Since 2009.
  •  Handling Editor of Heredity, one of two journals belonging to the Genetics Society. Since April 2012.
  • Member of the Editorial Board for the The Scientific World Journal (TSWJ). Since Nov 2011.

Previous positions

  • Lecturer in Cell Biology. Department of Cell Biology, UAB. December'08-September'13.
  • Post-doctoral Fellow. Università di Pavia, Pavia (Italy). Advisor: E. Giulotto. June’07-December’08.
  • Post-doctoral Fellow. University of Stellenbosch (South Africa). Advisor: T.J. Robinson. January’05-June’07.
  • Teaching assistant in Cell Biology. UAB (Spain). March’03-December’04.
  • Pre-doctoral Fellow. UAB (Spain). Advisors: M.Garcia and M. Ponsà. January’99-June’03.
  • Teaching assistant in Cell Biology. UAB (Spain). November ’98-December ’98.

Fellowships, Honors and Awards 

  • 2011  “Tram de Recerca 2005-2010”, Research Acreditation (period 2005-2010). Agència de la Qualitat Universitària (AQU).
  • 2010 “Profesor Titular de Universidad” Acreditation, Agencia Nacional de Evaluación de la Calidad y Acreditación (ANECA).
  • 2010  “Tram de Recerca 1999-2004”, Research Acreditation (period 1999-2004). Agència de la Qualitat Universitària (AQU).
  • 2009 “Professor Agregat” Acreditation, Agència de la Qualitat Universitària (AQU), Spain.
  • 2007 - 2008: Intra-European Fellowship from the FP6 EURATOM program supported by the European Commission
  • 2006 1st price for the best oral presentation at the Second Congress of the International Cytogenetic and Genome Society (ICGS). University of Canterbury, Kent (UK)
  • 2006 Invited professor, Cell Biology PhD program, Universitat Autònoma de Barcelona, Spain.
  • 2006 “Professor Lector” Acreditation, Agència de la Qualitat Universitària (AQU), Spain.
  • 2006 - 2007: Post-doctoral research fellowship supported by the Spanish Ministry of Education and Science (MEC) (Spain).
  • 2005 - 2006: Post-doctoral research fellowship supported by the University of Stellenbosch (South Africa).


I am interested at addressing a whole range of different evolutionary questions through a multidisciplinary approach, combining computational and experimental methods such as available genome databases and a battery of molecular, cytogenetic and cell biology, and by studying the genomes of different mammalian species. We propose to deepen and extend our past work on the study of evolutionary breakpoints in a wide range of mammalian species and to open new research avenues in the study of genome evolution (see our web site: http://grupsderecerca.uab.cat/evolgenom/en/content/research). 


Selected list of publications (for a complete list see http://grupsderecerca.uab.cat/evolgenom/en/content/research)


1.     M. Farré, T.J. Robinson, A. Ruiz-Herrera. An Integrative Breakage Model of genome architecture, reshuffling and evolution. Bioessays 37(5):479-88, 2015.

2.     J.M. Argyris, A. Ruiz-Herrera, P. Madriz-Masis, W. Sanseverino, J. Morata, M. Pujol M, S.E. Ramos-Onsins, J. Garcia-Mas. Use of targeted SNP selection for an improved anchoring of the melon (Cucumis melo L.) scaffold genome assembly. BMC Genomics 16:4, 2015

3.     M. Farré and A. Ruiz-Herrera*. Role of chromosomal reorganisations in the human-chimpanzee speciation. eLS (contribution by invitation) John Wiley & Sons, Ltd: Chichester, 2014. doi: 10.1002/9780470015902.a0025534.

4.     C. Aguado, M. Gayá-Vidal, S. Villatoro, M. Olive, D. Izquierdo, C. Giner-Delgado, A. Martínez-Fundichely, L. Capilla, A. Ruiz-Herrera, X. Estivill, M. Puig, M. Caceres. Large-scale validation and genotyping of human polymorphic inversions mediated by inverted repeats a high degree of recurrence. PLOS Genetics 10(3): e1004208, 2014. doi:10.1371/journal.pgen.1004208 (IF= 8.517, Q1 Genetics and Heredity).

5.     J. Segura, L. Ferretti, S. Ramos-Onsins, L. Capilla, M. Farré, F. Reis, M. Oliver-Bonet, H. Fernández-Bellon, T.J. Robinson, M. Garcia-Caldés, A. Ruiz-Herrera*. Insights into the mechanisms that affect meiotic recombination rates and crossover interference in eutherian mammals. Proc R Soc B 280 (1771): 1471-2954, 2013 doi:10.1098/rspb.2013.1945 (IF= 5.683, Q1 Biology/Evolutionary Biology/Ecology).

6.     Hormozdiari F, Konkel MK, Prado-Martinez J, Chiatante G, Herraez IH, Walker JA, Nelson B, Alkan C, Sudmant PH, Huddleston J, Catacchio CR, Ko A, Malig M, Baker C; Great Ape Genome Project (incl. A. Ruiz-Herrera), Marques-Bonet T, Ventura M, Batzer MA, Eichler EE. Rates and patterns of great ape retrotransposition. Proc Natl Acad Sci U S A 110(33):13457-62, 2013 doi: 10.1073/pnas.1310914110 (IF= 9.737, Q1 Multidisciplinary Sciences).

7.     J. Prado-Martinez, P. H. Sudmant, J. M. Kidd, H. Li, J. L. Kelley, B. Lorente-Galdos, K. R. Veeramah, A. Woerner, T. D. O’Connor, G. Santpere, A. Cagan, C. Theunert, F. Casals, H.  Laayouni, K. Munch, A. Hobolth, A. E. Halager, M. Malig, J. Hernandez-Rodriguez, I. Hernando-Herraez, K. Prüfer, M. Pybus, L. Johnstone, M. Lachmann, C. Alkan, D. Twigg, N. Petit, C. Baker, F. Hormozdiari, M. Fernandez-Callejo, M. Dabad, M. L. Wilson, L. Stevison, C. Camprubí, T. Carvalho, A. Ruiz-Herrera, L. Vives, M. Mele, T.Abello, I. Kondova, R. E. Bontrop, A. Pusey, F. Lankester, J. A. Kiyang, R. A. Berg, E. Lonsdorf, S. Myers, M. Ventura, P. Gagneux, D. Comas, H. Siegismund, J. Blanc, L. Agueda-Calpena, M. Gut, L. Fulton, S. A. Tishkoff, J. C. Mullikin, R. K. Wilson, I. G. Gut, M. K. Gonder, O. A. Ryder, B. H. Hahn, A. Navarro, J. M. Akey, J. Bertranpetit, D. Reich, T. Mailund, M. H. Schierup, C. Hvilsom, A. M. Andrés, J. Wall, C. D. Bustamante, M. Hammer, E. E. Eichler, T. Marques-Bonet. Great apes diversity and population history. Nature 99(7459):471-5, 2013 doi: 10.1038/nature12228 (IF= 38.597, Q1 Multidisciplinary Sciences).

8.     M. Farré, D. Micheletti, A. Ruiz-Herrera*. Recombination rates and chromosomal reorganizations between human and chimpanzee genomes - a new twist in the chromosomal speciation theory. Mol Biol Evol 30(4):853-64, 2013 (IF= 10.353, Q1 Genetics and Heredity).

9.     R. Reig-Viader, M. A. Brieño-Enríquez, N. Toran, Ll. Cabero, L. Khoriauli, E. Giulotto, M. Garcia-Caldés, A. Ruiz-Herrera*. Telomeric repeat-containing RNA and telomerase in human fetal oocytes. Human Reprod 28(2):414-22, 2013 (IF= 4.670, Q1 Reproductive Biology).

10.  A. Ruiz-Herrera, M. Farré, T.J. Robinson. Molecular cytogenetic and genomic insights to chromosomal evolution – Special issue on Molecular Cytogenetics: Karyotype evolution, Phylogenomics and Future prospects (contribution by invitation) Heredity, 108(1):28-36, 2012 (IF= 4.110, Q1 Genetics and Heredity/Ecology).

11.  M. Farré, M. Bosch, F. López-Giráldez, M. Ponsà, A. Ruiz-Herrera*. Assessing the role of tandem repeats in shaping the genomic architecture of great apes. PLOS One 6(11):e27239, 2011 (IF= 4.092, Q1 Multidisciplinary Sciences).

12.  R. Garcia-Cruz, S. Pacheco, M.A. Brieño, E. Steinberg, M. Mudry, A. Ruiz-Herrera*, M. Garcia-Caldés*. A comparative study of the recombination pattern in three species of Platyrrhini monkeys (Primates). Chromosoma 120(5):521-530, 2011 (IF= 3.847, Q2 Genetics and Heredity).

13.  A. Ruiz-Herrera, A. Smirnova, L. Khoriauli, S.G. Nergadze, C. Mondello, E. Giulotto. Gene amplification in human cells knocked down for RAD54. Genome Integrity 2(1):5, 2011.

14.  A. Ruiz-Herrera*, M. Farré, M. Ponsà, T.J. Robinson. Selection against Robertsonian fusions involving housekeeping genes in the house mouse: integrating data from gene expression arrays and chromosome evolution. Chromosome Res 18(7):801-808, 2010 (IF= 3.130, Q2 Genetics and Heredity).

15.  A. Salzano, N. Kochiashvili, S.G. Nergadze, L. Khoriauli, A. Smirnova, A. Ruiz-Herrera, C. Mondello, E. Giulotto. Enhanced gene amplification in human cells knocked down for DNA-PKcs. DNA Repair 8:19-28, 2009 (IF= 4.274, Q1 Genetics and Heredity/Toxicology).

16.  A. Ruiz-Herrera, S.G. Nergadze M. Santagostino, E. Giulotto. Telomeric repeats far from the ends: mechanisms of origin and role in evolution. Cytogenetics and Genome Research, special issue on Telomeres and Telomerase (contribution by invitation) 122: 219-228, 2008 (IF= 1.965, Q3 Genetics and Heredity).

17.  T.J. Robinson, A. Ruiz-Herrera, J.C. Avise. Hemiplasy and homoplasy in the karyotypic phylogenies of mammals. Proc Natl Acad Sci U S A 105: 14477-14481, 2008 (IF= 9.737, Q1 Multidisciplinary Sciences).

18.  T.J. Robinson, A. Ruiz-Herrera. Defining the ancestral eutherian karyotype: a cladistic interpretation of chromosome painting and genome sequence assembly data. Chromosome Res 16: 1133-1141, 2008 (IF= 3.405, Q2 Genetics and Heredity).

19.  A. Ruiz-Herrera*, T.J. Robinson. Evolutionary plasticity and cancer breakpoint in human chromosome 3: a review. BioEssays 30:1126-1137, 2008 (IF= 5.423, Q1 Biology).

20.  A. Ruiz-Herrera, T.J. Robinson. Afrotherian fragile sites, evolutionary breakpoints and phylogenetic inference from genomic assemblies. BMC Evol Biol 7(1):199, 2007 (IF= 4.040, Q2 Genetics and Heredity).

21.  P.D. Waters, A. Ruiz-Herrera, G. Dobigny, M. Garcia, T. J. Robinson. Sex chromosomes of basal placental mammals. Chromosoma 116(6):511-8, 2007 (IF= 3.340, Q2 Genetics and Heredity).

22.  A. Ruiz-Herrera, J. Castresana, T.J. Robinson. Is mammalian chromosomal evolution driven by regions of genome fragility? Genome Biol 7:R115, 2006 (IF= 10.288, Q1 Genetics and Heredity).

23.  T.J. Robinson, A. Ruiz-Herrera, L. Fröenicke. Dissecting the mammalian genome – new insights into chromosomal evolution. Trends in Genetics 22: 297-301, 2006 (IF= 9.772, Q1 Genetics and Heredity).

24.  N. Camats, A. Ruiz-Herrera, J.J. Parrilla, M. Acien, P. Payá, E. Giulotto, F. García, M. Garcia. Genomic instability in rat: breakpoints induced by ionizing radiation and interstitial telomeric-like sequences. Mutation Res, 595:156-166, 2006 (IF= 3.902, Q1 Genetics and Heredity/Toxicology).

25.  A. Ruiz-Herrera, F. García, M. Aguilera, M. Garcia, M. Ponsà. Comparative chromosome painting in Aotus reveals a highly derived evolution. Am J Primatol 65:73-85, 2005 (IF= 2.459, Q1 Zoology).

26.  A. Ruiz-Herrera, F. García, L. Fröenicke, M. Ponsà, J. Egozcue, M. Garcia, R. Stanyon. Conservation of aphidicolin-induced fragile sites in Papionini (Primates) species and humans. Chromosome Res 12(7):683-690, 2004 (IF= 3.405, Q2 Genetics and Heredity).

27.  A. Ruiz-Herrera, F. García, C. Azzalin, E. Giulotto, J. Egozcue, M. Ponsà, M.Garcia. Distribution of intrachromosomal telomeric sequences (ITS) on Macaca fascicularis (Primates) chromosomes and their implication for chromosome evolution. Human Genet 110:578-586, 2002 (IF= 4.633, Q1 Genetics and Heredity).