Samuel Peña-Díaz, Jordi Pujols, María Conde-Giménez, Anita Čarija, Esther Dalfo, Jesús García, Susanna Navarro, Francisca Pinheiro, Jaime Santos, Xavier Salvatella, Javier Sancho and Salvador Ventura (2019) ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization. Front. Mol. Neurosci., 12, 306 DOI: 10.3389/fnmol.2019.00306
Pujols J, Peña-Díaz S, F. Lázaro D, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Fleming Outeiro T, Dalfó E, Ventura S (2018) Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. PNAS, 115 (41) 10481-10486. DOI: 10.1073/pnas.1804198115
Pujols J, Pena-Diaz S, Ventura S (2017) AGGRESCAN3D: Toward the Prediction of the Aggregation Propensities of Protein Structures. Computational Drug Discovery and Design. Methods in Molecular Biology, vol 1762. Humana Press, New York, NY. DOI: 10.1007/978-1-4939-7756-7_21
Pujols J, Peña-Díaz S, Conde-Giménez M, Pinheiro F, Navarro S, Sancho J, Ventura S (2017) High-throughput screening methodology to identify alpha-synuclein aggregation inhibitors. Int J Mol Sci, 18:E478. DOI: 10.3390/ijms18030478
