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Title:
Conservation of anti-viral immunity in prokaryotes and eukaryotes
Abstract:
All cells, eukaryotic and prokaryotic, face the threat of viral infections and develop immune systems to fight them off. The constant arms race between cells and their viruses leads to the diversification of immune systems. Thus, hallmarks of immunity in diverse domains such as plants, animals or bacteria are completely different. However, the unveiling of novel anti-phage defense systems in prokaryotes lead us to revisit this paradigm. In this seminar, I will discuss the discovery of two new prokaryotic immune systems that show conservation in various degrees with eukaryotic ones and discuss the implications of these conservation for both prokaryotes and eukaryotes.